Episode 6

full
Published on:

25th Aug 2025

06: INSTANT TOOTH REPAIR? INSTANT WHITENING? FACT OR FICTION?

Is nano hydroxyapatite the breakthrough your teeth have been waiting for—or just another viral myth in oral care?

In this episode of Dental Formulator's Playbook, Dr. Rob and Tami tackle the growing buzz around nano hydroxyapatite (nano HAP) — a trending ingredient in oral care products. They break down the science behind nano HAP, separating fact from fiction, and address viral claims that it can instantly repair or whiten teeth. Dr. Rob explains what remineralization really means, why fluoride remains the gold standard for enamel protection, and where nano HAP fits into the conversation. From potential use for sensitivity relief or targeted use in children’s toothpaste, the hosts explore nano HAP’s possibilities and limits — and preview a deeper dive into specific nano HAP products in future episodes.

Highlights

  • What nano hydroxyapatite (nano HAP) is — and what science actually supports
  • Viral myths about nano HAP “instantly” repairing or whitening teeth debunked
  • The truth about remineralization: how it works and why it’s a slow, complex process
  • Why fluoride remains the most proven and effective enamel protector
  • Where nano HAP shows potential — including sensitivity relief and kids’ toothpaste formulations
  • Key limitations and gaps in research that consumers should understand
  • The difference between marketing claims and lab-verified benefits
  • Why nano HAP should complement — not replace — fluoride in oral care
  • Consumer tips for evaluating nano HAP-based products on the market
  • A preview of future episodes diving into specific nano HAP toothpaste brands

Connect with Dr. Rob (Robert L. Karlinsey, PhD)

🌐 Website: https://customdentalformulations.com/meet-dr-karlinsey

📄 Research Profile: https://www.researchgate.net/profile/Robert-Karlinsey

Show artwork for Dental Formulator's Playbook

About the Podcast

Dental Formulator's Playbook
The Dental Formulator’s Playbook is where science meets strategy in the world of oral health innovation. Hosted by Dr. Rob Karlinsey, a seasoned dental researcher and independent formulator, this podcast is your behind-the-scenes pass to what really goes into creating cutting-edge dental products.

Whether you're a dentist, a dental brand, or just someone curious about how toothpaste, rinses, and other oral care products are developed, you'll find practical insights and real-world takeaways in every episode. Dr. Karlinsey keeps it straightforward and engaging—no fluff, just clear, thoughtful explanations based on years of experience in the lab and the industry.

This show is all about helping dental professionals and product developers think differently, make better decisions, and stay ahead of the curve. If you care about science, results, and doing things the right way, you're in the right place.

About your host

Profile picture for Robert Karlinsey

Robert Karlinsey

Dr. Robert L. Karlinsey is a scientist and formulator with almost 20 years’ experience in dental research. He earned a BS in Physics (University of Scranton) and PhD in Chemical Physics (Indiana University), with postdoctoral work in physical chemistry (Indiana University). As a visiting assistant research professor at the Indiana University School of Dentistry, his research led to an impactful encounter with Dr. George Stookey, and shortly thereafter, the formation of Indiana Nanotech, LLC (now known as Custom Dental Formulations, LLC), of which he spearheaded all research and small-scale manufacturing efforts. Dr. Karlinsey is the inventor of Nanotech’s functionalized tricalcium phosphate systems, which continue to help generate over $100MM in global product sales for a major dental manufacturer. As Principal Investigator, his work has received significant funding through Federal (National Institutes of Health), State (Indiana and Texas), and industry grants and contracts. His research in patented calcium phosphate technologies continue to help generate over $100MM in global product sales. Previously, Dr. Karlinsey has served as Chief Scientific Officer at Therametric Technologies, Inc, and adjunct professor of chemistry at the University of Indianapolis.

Dr. Karlinsey addresses clients’ needs in preventive and cosmetic dentistry, including fluoride- and fluoride-free remineralization, antiplaque/gum health, whitening systems, and more. He is actively involved in clinical and laboratory research designs and performance-backed, customized oral care formulation solutions. And, whenever possible, he favors natural, nature-derived, and/or sustainably sourced ingredients