07: NANO HYDROXYAPATITE EXPOSED. The Science vs. The Hype

Is nano hydroxyapatite really the natural alternative to fluoride—or just clever marketing dressed up as science?

In this episode of Dental Formulator's Playbook, Dr. Rob and Tami continue their deep dive into nano hydroxyapatite (nano HAP) toothpaste — this time taking an even closer look at the evidence, marketing, and regulatory gaps surrounding the trendy ingredient. They dissect the claims that nano HAP is a fluoride replacement, exposing research biases, weak studies, and misleading advertising tactics that have fueled the hype. Dr. Rob explains why fluoride is still the gold standard for enamel remineralization and stresses the importance of evaluating every ingredient in a toothpaste — not just the active one.

🔥 Highlights ↠

↠ A closer look at the science (and lack thereof) behind nano HAP toothpaste claims

↠ Why nano HAP is often marketed as a “natural fluoride alternative” — and what’s missing from that narrative

↠ Regulatory differences between nano HAP and fluoride toothpastes, especially for children’s products

↠ Common marketing tactics and misleading claims surrounding nano HAP

↠ How research bias and underpowered studies shape consumer perception

↠ The importance of scrutinizing all toothpaste ingredients, not just the active component

↠ Why fluoride remains the gold standard for remineralization and cavity prevention

↠ Key questions consumers should ask before buying “fluoride-free” or “nano HAP” toothpastes

↠ Dr. Rob’s take on how nano HAP might fit into oral care — without replacing fluoride

Connect with Dr. Rob (Robert L. Karlinsey, PhD)

🌐 Website: https://customdentalformulations.com/meet-dr-karlinsey

📄 Research Profile: https://www.researchgate.net/profile/Robert-Karlinsey