Episode 26

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Published on:

12th Jan 2026

26: Not All Acids Are Equal - The Shocking Reason Oranges Damage Teeth More Than Apples with Dr. Rob Karlinsey

What if the real danger to your teeth isn’t that fruit is acidic, but that different fruit acids strip enamel in very different ways most people never learn about?

In this episode of Dental Formulator’s Playbook, Dr. Rob and Tami break down the chemistry behind fruit acids and their real impact on dental erosion. While fruits are often grouped together as “acidic,” the hosts explain why citric acid, malic acid, and tartaric acid behave very differently once they interact with enamel, saliva, and calcium.

Using clear chemistry explanations and published research, the conversation explores why oranges pose a higher erosion risk than apples, how calcium binding changes as pH shifts in the mouth, and why certain acids are routinely used in dental erosion testing models. The episode also covers practical, evidence-based strategies to reduce acid damage without avoiding healthy foods altogether.

🔍 Episode Highlights

  1. Why acidic foods are not equally damaging to teeth
  2. The difference between dental erosion and dental caries
  3. Citric acid vs malic acid vs tartaric acid explained simply
  4. How calcium binding strength determines erosion risk
  5. Why citric acid is the standard acid used in erosion research models
  6. How pH shifts in the mouth amplify mineral loss
  7. The role of EDTA and why its chelation strength matters
  8. Why calcium-fortified beverages reduce enamel damage
  9. How wine and sports drinks contribute to dental erosion
  10. The science behind brushing timing after acidic exposure

🧪 Key Takeaways

  1. Different fruits expose teeth to different acids, which vary in erosive potential
  2. Apples primarily contain malic acid, which has lower calcium-binding strength
  3. Oranges primarily contain citric acid, which is more erosive due to stronger calcium binding
  4. Grapes primarily contain tartaric acid, which behaves more similarly to citric acid than malic acid
  5. Citric acid contains three carboxylic acid groups, allowing it to bind calcium more aggressively at oral pH
  6. Stronger calcium binding increases enamel mineral loss compared to acids with fewer binding sites
  7. EDTA binds calcium far more strongly than fruit acids and must be carefully managed in dental formulations
  8. Citrus fruits and juices pose a higher erosion risk than apples
  9. Calcium-rich foods and beverages can act as sacrificial calcium to reduce enamel damage
  10. Calcium-fortified orange juice may lessen erosive effects compared to non-fortified versions
  11. Brushing immediately after acidic foods or drinks increases enamel wear
  12. Waiting at least 30 minutes before brushing allows saliva to restore pH and protect enamel
  13. Eating cheese, yogurt, or other calcium-containing foods after acid exposure supports remineralization
  14. Chewing sugar-free gum or having a sugar-free mint stimulates saliva and enhances natural protection
  15. Saliva plays a critical role in buffering acids and maintaining enamel integrity

📲 Connect with Dr. Rob (Robert L. Karlinsey, PhD)

🌐 Website: customdentalformulations.com

📄 Research Profile: Robert Karlinsey on ResearchGate

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About the Podcast

Dental Formulator's Playbook
The Dental Formulator’s Playbook is where science meets strategy in the world of oral health innovation. Hosted by Dr. Rob Karlinsey, a seasoned dental researcher and independent formulator, this podcast is your behind-the-scenes pass to what really goes into creating cutting-edge dental products.

Whether you're a dentist, a dental brand, or just someone curious about how toothpaste, rinses, and other oral care products are developed, you'll find practical insights and real-world takeaways in every episode. Dr. Karlinsey keeps it straightforward and engaging—no fluff, just clear, thoughtful explanations based on years of experience in the lab and the industry.

This show is all about helping dental professionals and product developers think differently, make better decisions, and stay ahead of the curve. If you care about science, results, and doing things the right way, you're in the right place.

About your host

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Robert Karlinsey

Dr. Robert L. Karlinsey is a scientist and formulator with almost 20 years’ experience in dental research. He earned a BS in Physics (University of Scranton) and PhD in Chemical Physics (Indiana University), with postdoctoral work in physical chemistry (Indiana University). As a visiting assistant research professor at the Indiana University School of Dentistry, his research led to an impactful encounter with Dr. George Stookey, and shortly thereafter, the formation of Indiana Nanotech, LLC (now known as Custom Dental Formulations, LLC), of which he spearheaded all research and small-scale manufacturing efforts. Dr. Karlinsey is the inventor of Nanotech’s functionalized tricalcium phosphate systems, which continue to help generate over $100MM in global product sales for a major dental manufacturer. As Principal Investigator, his work has received significant funding through Federal (National Institutes of Health), State (Indiana and Texas), and industry grants and contracts. His research in patented calcium phosphate technologies continue to help generate over $100MM in global product sales. Previously, Dr. Karlinsey has served as Chief Scientific Officer at Therametric Technologies, Inc, and adjunct professor of chemistry at the University of Indianapolis.

Dr. Karlinsey addresses clients’ needs in preventive and cosmetic dentistry, including fluoride- and fluoride-free remineralization, antiplaque/gum health, whitening systems, and more. He is actively involved in clinical and laboratory research designs and performance-backed, customized oral care formulation solutions. And, whenever possible, he favors natural, nature-derived, and/or sustainably sourced ingredients